The MOST Options System is designed to enable patients facing severe bone loss of the knee or hip to regain use of their limbs and provides the potential for restoration of function.

The system goes beyond the requirements of a rotating hinge and provides the surgeon intraoperative flexibility to address a patient’s individual situation.

The anatomic, modular MOST Options System gives you maximum intraoperative flexibility in implant selection, connection, and fixation. The system offers a wide variety of implant sizes, segments, adapters, and stems to accommodate these complex cases.

The MOST Options System helps patients with problems that require surgery due to:

• Bone tumors (including benign, metastatic, and sarcoma cases)
• Revision cases requiring extensive bone resection
• Bone loss from traumatic injury
• Severe deformity such as osteomyelitis
• Damage to ligamentous supports

The Total Femoral Segment component is manufactured from Tivanium^® Ti-6Al-4V Alloy and is available with or without a porous coating. It consists of a single length and 2 MOST male tapers to facilitate its use with Proximal and Distal Femoral Components and other segments.

Segments are manufactured from Ti-6Al-4V Alloy and are available in a variety of lengths to allow the surgeon to restore the leg length as closely as possible. They have a MOST male and a MOST female taper to facilitate their use with Proximal and Distal Femoral, Proximal Tibial, and I/M Stem Components and other segments.

The All-Poly Patella has an elliptical shape and is manufactured from UHMWPE.

Treatment of soft-tissue cancers of the lower limb has developed significantly over the past 30 years. Limb salvage procedures are more frequently being used to treat tumors of the lower limb. In the past, the original treatment options were limited and amputation was typically the option of choice to manage these tumors. The possibility of tumor recurrence and the possibility of metastasis limited many developments in treatment.

Advancements in chemotherapy and imaging technologies provided a door for limb salvage treatment. Chemotherapy has helped by reducing the risks associated with recurrence and metastasis. Computed tomography (CT) imaging and magnetic resonance imaging (MRI) have aided doctors by providing more detailed and precise images of tumors.

The first prostheses designed for limb salvage around the knee were constrained hinge knee systems. These first systems functioned like a door hinge and only provided extension and flexion. The constrained hinge knees had limited success and would frequently loosen. Additionally, the constrained designs could not manage rotational stress and transferred these stresses to the bone/implant interface. These stresses to the bone/implant interface were one of the key factors in early loosening for the first-generation hinged knees.

The MOST Options System also offers a variety of options for attaching the implant to the bone. These options are designed to ensure that the implant is able to fit the patient’s anatomy and is well-secured. Another important feature incorporated into the MOST Options System is the resection options. The system provides bone-conserving options so bone stock can be preserved.

Sterility
Gamma irradiation is indicated by the symbol on the labeling. These devices remain sterile as long as the package integrity has not been violated. Inspect each package prior to use and do not use the component if any seal or cavity is damaged or breached or if the expiration date has been exceeded. Once opened, the component must be used or discarded.

Resterilization Information
These devices may not be resterilized.

MOST Option System for Severe Bone Loss